The cannabidiol is a popular natural remedy used for many common ailments.
Better known as CBD, it is one of over 100 chemical compounds known as cannabinoids found in the cannabis or marijuana plant, Cannabis sativa.
Tetrahydrocannabinol
(THC) is the main psychoactive cannabinoid found in cannabis, and
causes the sensation of getting “high” that’s often associated with
marijuana. However, unlike THC, CBD is not psychoactive.
This
quality makes CBD an appealing option for those who are looking for
relief from pain and other symptoms without the mind-altering effects of
marijuana or certain pharmaceutical drugs.
CBD oil is made by extracting CBD from the cannabis plant, then diluting it with a carrier oil like coconut or hemp seed oil.
It’s
gaining momentum in the health and wellness world, with some scientific
studies confirming it may ease symptoms of ailments like chronic pain
and anxiety.
Here are seven health benefits of CBD oil that are backed by scientific evidence.
1. It Can Relieve Pain
Marijuana has been used to treat pain as far back as 2900 B.C.
More
recently, scientists have discovered that certain components of
marijuana, including CBD, are responsible for its pain-relieving
effects.
The
human body contains a specialized system called the endocannabinoid
system (ECS), which is involved in regulating a variety of functions
including sleep, appetite, pain and immune system response.
The body produces endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors in your nervous system.
Studies
have shown that CBD may help reduce chronic pain by impacting
endocannabinoid receptor activity, reducing inflammation and interacting
with neurotransmitters.
For
example, one study in rats found that CBD injections reduced pain
response to surgical incision, while another rat study found that oral
CBD treatment significantly reduced sciatic nerve pain and inflammation.
Several
human studies have found that a combination of CBD and THC is effective
in treating pain related to multiple sclerosis and arthritis.
An
oral spray called Sativex, which is a combination of THC and CBD, is
approved in several countries to treat pain related to multiple
sclerosis.
One
study of 47 people with multiple sclerosis examined the effects of
taking Sativex for one month. The participants experienced improvements
in pain, walking, and muscle spasms. Still, the study didn’t include any
control group and placebo effects cannot be ruled out.
Another
study found that Sativex significantly improved pain during movement,
pain at rest and sleep quality in 58 people with rheumatoid arthritis.
2. Could Reduce Depression And Anxiety
Anxiety and depression are common mental health disorders that can have devastating impacts on health and well-being.
According
to the World Health Organization, depression is the single largest
contributor to disability worldwide, while anxiety disorders are ranked
sixth (9).
Anxiety and
depression are usually treated with pharmaceutical drugs, which can
cause a number of side effects including drowsiness, agitation,
insomnia, sexual dysfunction and headache.
What’s more, medications like benzodiazepines can be addictive and may lead to substance abuse.
CBD
oil has shown promise as a treatment for both depression and anxiety,
leading many who live with these disorders to become interested in this
natural approach.
In
one Brazilian study, 57 men received either oral CBD or a placebo 90
minutes before they underwent a simulated public speaking test. The
researchers found that a 300-mg dose of CBD was the most effective at
significantly reducing anxiety during the test.
The placebo, a 150-mg dose of CBD, and a 600-mg dose of CBD had little to no effect on anxiety.
CBD oil has even been used to safely treat insomnia and anxiety in children with post-traumatic stress disorder.
CBD has also shown antidepressant-like effects in several animal studies.
These
qualities are linked to CBD’s ability to act on the brain’s receptors
for serotonin, a neurotransmitter that regulates mood and social
behavior.
3. It Can Alleviate Cancer-Related Symptoms
CBD may help reduce symptoms related to cancer and side effects related to cancer treatment, like nausea, vomiting and pain.
One
study looked at the effects of CBD and THC in 177 people with
cancer-related pain who did not experience relief from pain medication.
Those
treated with an extract containing both compounds experienced a
significant reduction in pain compared to those who received only THC
extract.
CBD
may also help reduce chemotherapy-induced nausea and vomiting, which
are among the most common chemotherapy-related side effects for those
with cancer.
Though
there are drugs that help with these distressing symptoms, they are
sometimes ineffective, leading some people to seek alternatives.
A
study of 16 people undergoing chemotherapy found that a one-to-one
combination of CBD and THC administered via mouth spray reduced
chemotherapy-related nausea and vomiting better than standard treatment
alone.
Some
test-tube and animal studies have even shown that CBD may have
anticancer properties. For example, one test-tube study found that
concentrated CBD induced cell death in human breast cancer cells.
Another study showed that CBD inhibited the spread of aggressive breast cancer cells in mice.
However,
these are test-tube and animal studies, so they can only suggest what
might work in people. More studies in humans are needed before
conclusions can be made.
4. It May Reduce Acne
CBD may help reduce symptoms related to cancer and side effects related to cancer treatment, like nausea, vomiting and pain.
One
study looked at the effects of CBD and THC in 177 people with
cancer-related pain who did not experience relief from pain medication.
Those
treated with an extract containing both compounds experienced a
significant reduction in pain compared to those who received only THC
extract.
CBD
may also help reduce chemotherapy-induced nausea and vomiting, which
are among the most common chemotherapy-related side effects for those
with cancer.
Though
there are drugs that help with these distressing symptoms, they are
sometimes ineffective, leading some people to seek alternatives.
A
study of 16 people undergoing chemotherapy found that a one-to-one
combination of CBD and THC administered via mouth spray reduced
chemotherapy-related nausea and vomiting better than standard treatment
alone.
Some
test-tube and animal studies have even shown that CBD may have
anticancer properties. For example, one test-tube study found that
concentrated CBD induced cell death in human breast cancer cells.
Another study showed that CBD inhibited the spread of aggressive breast cancer cells in mice.
However,
these are test-tube and animal studies, so they can only suggest what
might work in people. More studies in humans are needed before
conclusions can be made.
5. It Might Have Neuroprotective Properties
Researchers
believe that CBD’s ability to act on the endocannabinoid system and
other brain signaling systems may provide benefits for those with
neurological disorders.
In
fact, one of the most studied uses for CBD is in treating neurological
disorders like epilepsy and multiple sclerosis. Though research in this
area is still relatively new, several studies have shown promising
results.
Sativex,
an oral spray consisting of CBD and THC, has been proven to be a safe
and effective way to reduce muscle spasticity in people with multiple
sclerosis.
One
study found that Sativex reduced spasms in 75% of 276 people with
multiple sclerosis who were experiencing muscle spasticity that was
resistant to medications.
Another
study gave 214 people with severe epilepsy 0.9–2.3 grams of CBD oil per
pound (2–5 g/kg) of body weight. Their seizures reduced by a median of
36.5%
One
more study found that CBD oil significantly reduced seizure activity in
children with Dravet syndrome, a complex childhood epilepsy disorder,
compared to a placebo.
However,
it’s important to note that some people in both these studies
experienced adverse reactions associated with CBD treatment, such as
convulsions, fever and fatigue.
CBD has also been researched for its potential effectiveness in treating several other neurological diseases.
For
example, several studies have shown that treatment with CBD improved
quality of life and sleep quality for people with Parkinson’s disease.
Additionally,
animal and test-tube studies have shown that CBD may decrease
inflammation and help prevent the neurodegeneration associated with
Alzheimer’s disease.
In
one long-term study, researchers gave CBD to mice genetically
predisposed to Alzheimer’s disease, finding that it helped prevent
cognitive decline.
6. It Could Benefit Heart Health
Recent
research has linked CBD with several benefits for the heart and
circulatory system, including the ability to lower high blood pressure.
High
blood pressure is linked to higher risks of a number of health
conditions, including stroke, heart attack and metabolic syndrome.
Studies indicate that CBD may be able to help with high blood pressure.
One
recent study treated nine healthy men with one dose of 600 mg of CBD
oil and found it reduced resting blood pressure, compared to a placebo.
The
same study also gave the men stress tests that normally increase blood
pressure. Interestingly, the single dose of CBD led the men to
experience a smaller blood pressure increase than normal in response to
these tests.
Researchers
have suggested that the stress- and anxiety-reducing properties of CBD
are responsible for its ability to help lower blood pressure.
Additionally,
several animal studies have demonstrated that CBD may help reduce the
inflammation and cell death associated with heart disease due to its
powerful antioxidant and stress-reducing properties.
For
example, one study found that treatment with CBD reduced oxidative
stress and prevented heart damage in diabetic mice with heart disease.
7. Other Potential Benefits
CBD has been studied for its role in treating a number of health issues other than those outlined above.
Though more studies are needed, CBD is thought to provide the following health benefits:
- Antipsychotic effects: Studies suggest that CBD may help people with schizophrenia and other mental disorders by reducing psychotic symptoms.
- Substance abuse treatment: CBD has been shown to modify circuits in the brain related to drug addiction. In rats, CBD has been shown to reduce morphine dependence and heroin-seeking behavior.
- Anti-tumor effects: In test-tube and animal studies, CBD has demonstrated anti-tumor effects. In animals, it has been shown to prevent the spread of breast, prostate, brain, colon and lung cancer.
- Diabetes prevention: In diabetic mice, treatment with CBD reduced the incidence of diabetes by 56% and significantly reduced inflammation.
Likely Side Effects
CBD has been studied for its role in treating a number of health issues other than those outlined above.
Though more studies are needed, CBD is thought to provide the following health benefits:
- Antipsychotic effects: Studies suggest that CBD may help people with schizophrenia and other mental disorders by reducing psychotic symptoms
- Substance abuse treatment: CBD has been shown to modify circuits in the brain related to drug addiction. In rats, CBD has been shown to reduce morphine dependence and heroin-seeking behavior
- Anti-tumor effects: In test-tube and animal studies, CBD has demonstrated anti-tumor effects. In animals, it has been shown to prevent the spread of breast, prostate, brain, colon and lung cancer.
- Diabetes prevention: In diabetic mice, treatment with CBD reduced the incidence of diabetes by 56% and significantly reduced inflammation
Conclusion
CBD
oil has been studied for its potential role in easing symptoms of many
common health issues, including anxiety, depression, acne and heart
disease.
For those with cancer, it may even provide a natural alternative for pain and symptom relief.
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